Monday, August 30, 2010
From clinical to retail pharmacy
Saturday, August 28, 2010
Diosmin For Circulation & Vein Benefits
For ages, cranberry has been used for the prevention and treatment of urinary tract infections. Research suggests that it prevents bacteria from adhering to host cell surface membranes. It was used by Native Americans to treat ailments of the bladder and kidneys. The cranberry was documented in the 17th century as a treatment for several ailments, including:
* Blood disorders
* Liver problems, vomiting and stomach ailments
* Loss of appetite
* Scurvy
*Cancer
Cranberry was used as an effective treatment for urinary tract infections long before antibiotics were invented. It is still recommended by physicians to be used in conjunction with a prescribed round of antibiotics for treating bladder infections.
Important Facts
Statistically, one in every five women in the United States suffers from bladder infections in her lifetime. Three percent of these women suffer from recurrent urinary tract infections (UTIs). Approximately 11 million women each year receive medications to treat UTIs. Studies show that women with a history of bladder infections can reduce the frequency of those infections by regularly drinking cranberry juice.
There have been no significant reactions discovered between cranberry and prescription drugs. Drinking cranberry juice a minimum of three times per day during treatment of a bladder infection will increase the need to urinate. This helps your body to rid itself of the infection through ingestion and expulsion of fluids.
Pharmacology of Cranberry
The use of cranberry for medicinal purposes has been the subject of many scientific discussions. At first, it was thought that acidification of the urine assisted in creating an antibacterial effect. However, the primary reason that cranberry works so well for treating bladder infections is its prevention of bacterial adhesion to cell walls. It also prevents adherence by other gram-negative uropathogens that cause infection. Cranberry's ability to inhibit the adherence of bacteria has been shown through in vitro research.
Other Uses
One study showed that the same property in cranberry juice that prevents bladder infections also aids in dental plaque prevention. Additionally, cranberry has been discovered to be a recommended treatment for Candida (yeast) infections.
Further in vitro studies show that cranberry has an inhibiting effect on certain types of fungi. However, there are no human trials that indicate its effectiveness in treating fungal infections when used alone.
Symptoms of a Bladder Infection
The most common symptom of an oncoming bladder infection is feeling a constant, urgent need to empty the bladder. This feeling is present even when there is little or no fluid in the bladder. Other symptoms may include:
* Frequent urination
* Dysuria (burning or painful urination)
* Bladder spasms
* Cloudy urine
* Bloody urine
* Foul-smelling urine
* Mild fever
A bladder infection that has gone untreated for an extended period of time could turn into a kidney infection. This brings with it much more serious symptoms which may include fever, chills and nausea. You may also experience cloudy or bloody urine, painful urination and abdominal pain. A common telltale sign of kidney infection is back pain just above the waist.
If you are experiencing any of these symptoms, it is wise to contact your physician. Bladder infection symptoms will not go away by themselves. They will continue to worsen, and your infection will become much more serious. Treatment for bladder infections is quick and easy. The sooner you begin the better.
If you suspect that you are about to experience a bladder infection, begin a regimen of drinking cranberry juice or supplement at least three times a day and make an appointment with your doctor.
Preventing Bladder Infections
There are several precautions you can take to prevent bladder infections. Some may seem obvious or silly, but after your first infection you will think very differently. Some of these precautions include:
* Wipe from front to back after urination or a bowel movement. This prevents the spread of bacteria.
* Go to the bathroom frequently. Holding urine in the bladder for long periods of time invites an infection.
* Keep the genital area clean and dry. Avoid prolonged moisture in the area.
* Avoid frequent bubble baths. They can cause vaginal irritation.
Diosmin For Circulation & Vein Benefits
* Try to urinate soon after sexual activity. If lubricants are used, use only those that are water-soluble.
* Underwear with a cotton crotch will aid in infection prevention as well.
Drink a lot of water throughout the day. Also, drink cranberry juice or cranberry supplement to keep the urine acidic. This will prevent natural bacteria from multiplying as frequently, thus avoiding bladder infection.
* Blood disorders
* Liver problems, vomiting and stomach ailments
* Loss of appetite
* Scurvy
*Cancer
Cranberry was used as an effective treatment for urinary tract infections long before antibiotics were invented. It is still recommended by physicians to be used in conjunction with a prescribed round of antibiotics for treating bladder infections.
Important Facts
Statistically, one in every five women in the United States suffers from bladder infections in her lifetime. Three percent of these women suffer from recurrent urinary tract infections (UTIs). Approximately 11 million women each year receive medications to treat UTIs. Studies show that women with a history of bladder infections can reduce the frequency of those infections by regularly drinking cranberry juice.
There have been no significant reactions discovered between cranberry and prescription drugs. Drinking cranberry juice a minimum of three times per day during treatment of a bladder infection will increase the need to urinate. This helps your body to rid itself of the infection through ingestion and expulsion of fluids.
Pharmacology of Cranberry
The use of cranberry for medicinal purposes has been the subject of many scientific discussions. At first, it was thought that acidification of the urine assisted in creating an antibacterial effect. However, the primary reason that cranberry works so well for treating bladder infections is its prevention of bacterial adhesion to cell walls. It also prevents adherence by other gram-negative uropathogens that cause infection. Cranberry's ability to inhibit the adherence of bacteria has been shown through in vitro research.
Other Uses
One study showed that the same property in cranberry juice that prevents bladder infections also aids in dental plaque prevention. Additionally, cranberry has been discovered to be a recommended treatment for Candida (yeast) infections.
Further in vitro studies show that cranberry has an inhibiting effect on certain types of fungi. However, there are no human trials that indicate its effectiveness in treating fungal infections when used alone.
Symptoms of a Bladder Infection
The most common symptom of an oncoming bladder infection is feeling a constant, urgent need to empty the bladder. This feeling is present even when there is little or no fluid in the bladder. Other symptoms may include:
* Frequent urination
* Dysuria (burning or painful urination)
* Bladder spasms
* Cloudy urine
* Bloody urine
* Foul-smelling urine
* Mild fever
A bladder infection that has gone untreated for an extended period of time could turn into a kidney infection. This brings with it much more serious symptoms which may include fever, chills and nausea. You may also experience cloudy or bloody urine, painful urination and abdominal pain. A common telltale sign of kidney infection is back pain just above the waist.
If you are experiencing any of these symptoms, it is wise to contact your physician. Bladder infection symptoms will not go away by themselves. They will continue to worsen, and your infection will become much more serious. Treatment for bladder infections is quick and easy. The sooner you begin the better.
If you suspect that you are about to experience a bladder infection, begin a regimen of drinking cranberry juice or supplement at least three times a day and make an appointment with your doctor.
Preventing Bladder Infections
There are several precautions you can take to prevent bladder infections. Some may seem obvious or silly, but after your first infection you will think very differently. Some of these precautions include:
* Wipe from front to back after urination or a bowel movement. This prevents the spread of bacteria.
* Go to the bathroom frequently. Holding urine in the bladder for long periods of time invites an infection.
* Keep the genital area clean and dry. Avoid prolonged moisture in the area.
* Avoid frequent bubble baths. They can cause vaginal irritation.
* Try to urinate soon after sexual activity. If lubricants are used, use only those that are water-soluble.
* Underwear with a cotton crotch will aid in infection prevention as well.
Drink a lot of water throughout the day. Also, drink cranberry juice or cranberry supplement to keep the urine acidic. This will prevent natural bacteria from multiplying as frequently, thus avoiding bladder infection.
Tribulus Terrestris- Gokshura - Effective Herbal Urinary Disinfectant
Family :- Zygophyllaceae
Common names :- Small Caltrops, Tribulus
Sanskrit- Gokshura ('cow scratcher'), Hindi- Gokharu, English- Land Caltrops and Puncture Vine, Cow hage; Telugu- Palleru, Tamil- Neringil, Bengali- Gokuri, Marathi- Kante gokaru.
Synonyms :- Trikantaka, Svadukantaka, Ikshugandhika, Svadanstra, Palankasa.
Classical Categorization :
Caraka: Shothhara, Mutravirechaniya, Krmighana
Susruta : Laghu panchamula, Vidarigandhadi, Viratarvadi
Vagbhata : Vidarigandhadi
General description :
Tribulus terrestris or Gokshura is identified as the best drug for Mutrakriccha i.e. Dysuria and vata rogas i.e. diseases caused by the vitiation of vata dosha. It is one of the herbs which is both Mutrala and shothahara which means it is both a diuretic as well as an anti-inflammatory drug.
Properties:
Rasa : Madhura
Guna: Guru, Snigdha
Veerya: Shita
Vipaka: madhura
Karma: Vata-pitta hara, vrishya, mutrala, rasayana.
Botanical Description :
Gokshura is a annual or perennial herb with many spreading slender branches, the immature portions covered in a fine silky hair.
Leaves- The leaves are stipulate, oppositely arranged, usually unequal, abruptly pinnate, with 4-7 eight simple leaflets that are almost sessile to the leaf stem.
Flowers- Solitary, axillary or leaf- opposed, yellow or white. The solitary yellow flowers have five petals, and are borne in the leaf axils
Fruits- The fruits are globose, hairy, 5-angled, spinous with two long and two short spines on each cocci, each cocci containing several seeds.
Seeds- Obliquely pendulous.
Flowers and Fruits appear during April- August.
Parts used : Roots and Fruits.
Major Chemical Constituents :
Roots: Campesterol, B-sitisterol and stigmasterol
Fruits: chlorogenin, diosgenin, rutin, rhamnose
Aerial parts : astragalin, dioscin, diosgenin, hecogenin, ruscogenin, trillin, furostanol glycoside, spirosterol saponin, terrestrosides A-F saponins C and G etc.
Pharmacology:
Tribestan is a completely natural non-hormonal herbal (phytochemical) biostimulator derived from the plant Tribulus terrestris, which contains predominantly saponins of furostanol type, with prevailing quantity of protodioscin. It is a natural herbal alternative to synthetic anabolic hormones without any clinically proven toxic effects.
Administration of Tribestan leads to increased muscle mass by activating the enzyme associated with energy metabolism. At the same time it has also been reported to have the ability to increase of the body's natural endogenous testosterone and lutenizing hormone (LH), DHEA, and estrogen levels. With the increase of the body's natural endogenous testosterone level, it can help stimulating sexual functions.
Indications :
1)Mutrakriccha i.e. dysuria (painful/burning micturation)
2)Ashmari i.e. urolithiasis (kidney stones)
3)Crystalluria i.e. presence of crystals in urine.
4)Prameha (diabetes)
5)Hrdroga (cardiovascular disease)
6)Arsha (haemorrhoids)
7)Swasa-Kasa (cough, dyspnoea, asthmatic conditions etc.)
8)Klaibya (spermatorrhea, impotence, frigidity, infertility, venereal diseases etc.)
9)Kidney dysfunction, nephritis.
10)Recurrent urinary tract infections.
Therapuetic uses :
Various research works have been conducted on gokshura which revealed that this is a nephro-protective, hepato-protective drug. The decoction of its fuits and roots have found to be diuretic It also have Anti-Cancer and Lithotriptic properties.
The Vajikarna or Aphrodisiac property of Gokshura is well established by now. It has been extensively used for sexual dysfunction in both males and females. It’s a libido and sexual behaviour enhancer which results in longer orgasms and climaxes.
Ancient science of Ayurveda identifies that this herb has an excellent positive effect on the urinary tract thereby soothing the 'Vrikka' - the Kidneys. It is considered to be a general health tonic and urinary tract disinfectant. It is most often used as a urinary genital support. It increases the energy levels and stamina of a person, thus it has become popular in increasing sports performance. In Ayurveda, it is called as 'Rasayana' meaning rejuvenating the health. This herb improves the longevity of a person by offering strength to the body organs and muscles and increasing the immunity. With the combination of other rasayana drugs, this drug makes an excellent rejuvenating formula for the body.
Dosage:
Kwatha or Decoction : 50-100 ml, twice daily
Churana or Powder: 3-6 g, twice daily
Important preparations of Gokshura :
Gokshuradi guggulu, Gokshuradi kwatha, Gokshuradi rasayana, Gokshuradyavleha, Dasmoolarishta
Common names :- Small Caltrops, Tribulus
Sanskrit- Gokshura ('cow scratcher'), Hindi- Gokharu, English- Land Caltrops and Puncture Vine, Cow hage; Telugu- Palleru, Tamil- Neringil, Bengali- Gokuri, Marathi- Kante gokaru.
Synonyms :- Trikantaka, Svadukantaka, Ikshugandhika, Svadanstra, Palankasa.
Classical Categorization :
Caraka: Shothhara, Mutravirechaniya, Krmighana
Susruta : Laghu panchamula, Vidarigandhadi, Viratarvadi
Vagbhata : Vidarigandhadi
General description :
Tribulus terrestris or Gokshura is identified as the best drug for Mutrakriccha i.e. Dysuria and vata rogas i.e. diseases caused by the vitiation of vata dosha. It is one of the herbs which is both Mutrala and shothahara which means it is both a diuretic as well as an anti-inflammatory drug.
Properties:
Rasa : Madhura
Guna: Guru, Snigdha
Veerya: Shita
Vipaka: madhura
Karma: Vata-pitta hara, vrishya, mutrala, rasayana.
Botanical Description :
Gokshura is a annual or perennial herb with many spreading slender branches, the immature portions covered in a fine silky hair.
Leaves- The leaves are stipulate, oppositely arranged, usually unequal, abruptly pinnate, with 4-7 eight simple leaflets that are almost sessile to the leaf stem.
Flowers- Solitary, axillary or leaf- opposed, yellow or white. The solitary yellow flowers have five petals, and are borne in the leaf axils
Fruits- The fruits are globose, hairy, 5-angled, spinous with two long and two short spines on each cocci, each cocci containing several seeds.
Seeds- Obliquely pendulous.
Flowers and Fruits appear during April- August.
Parts used : Roots and Fruits.
Major Chemical Constituents :
Roots: Campesterol, B-sitisterol and stigmasterol
Fruits: chlorogenin, diosgenin, rutin, rhamnose
Aerial parts : astragalin, dioscin, diosgenin, hecogenin, ruscogenin, trillin, furostanol glycoside, spirosterol saponin, terrestrosides A-F saponins C and G etc.
Pharmacology:
Tribestan is a completely natural non-hormonal herbal (phytochemical) biostimulator derived from the plant Tribulus terrestris, which contains predominantly saponins of furostanol type, with prevailing quantity of protodioscin. It is a natural herbal alternative to synthetic anabolic hormones without any clinically proven toxic effects.
Administration of Tribestan leads to increased muscle mass by activating the enzyme associated with energy metabolism. At the same time it has also been reported to have the ability to increase of the body's natural endogenous testosterone and lutenizing hormone (LH), DHEA, and estrogen levels. With the increase of the body's natural endogenous testosterone level, it can help stimulating sexual functions.
Indications :
1)Mutrakriccha i.e. dysuria (painful/burning micturation)
2)Ashmari i.e. urolithiasis (kidney stones)
3)Crystalluria i.e. presence of crystals in urine.
4)Prameha (diabetes)
5)Hrdroga (cardiovascular disease)
6)Arsha (haemorrhoids)
7)Swasa-Kasa (cough, dyspnoea, asthmatic conditions etc.)
8)Klaibya (spermatorrhea, impotence, frigidity, infertility, venereal diseases etc.)
9)Kidney dysfunction, nephritis.
10)Recurrent urinary tract infections.
Therapuetic uses :
Various research works have been conducted on gokshura which revealed that this is a nephro-protective, hepato-protective drug. The decoction of its fuits and roots have found to be diuretic It also have Anti-Cancer and Lithotriptic properties.
The Vajikarna or Aphrodisiac property of Gokshura is well established by now. It has been extensively used for sexual dysfunction in both males and females. It’s a libido and sexual behaviour enhancer which results in longer orgasms and climaxes.
Ancient science of Ayurveda identifies that this herb has an excellent positive effect on the urinary tract thereby soothing the 'Vrikka' - the Kidneys. It is considered to be a general health tonic and urinary tract disinfectant. It is most often used as a urinary genital support. It increases the energy levels and stamina of a person, thus it has become popular in increasing sports performance. In Ayurveda, it is called as 'Rasayana' meaning rejuvenating the health. This herb improves the longevity of a person by offering strength to the body organs and muscles and increasing the immunity. With the combination of other rasayana drugs, this drug makes an excellent rejuvenating formula for the body.
Dosage:
Kwatha or Decoction : 50-100 ml, twice daily
Churana or Powder: 3-6 g, twice daily
Important preparations of Gokshura :
Gokshuradi guggulu, Gokshuradi kwatha, Gokshuradi rasayana, Gokshuradyavleha, Dasmoolarishta
Aromatherapy – Using Nature’s Aroma To Cure
Aromachology studies the effects of different aromas on human behavior. Certain aromas are believed to have relaxing effect on our mind and body. Aromatherapy includes not only the use of essential oils, but also absolutes, hydrosols, infusion, phytoncides, and carrier oils. The absolutes are oils extracted by superficial fluid extraction, like the rose absolute. Hydrosols, like the rose water, are aqueous by-products after distillation. Infusions are the aqueous solutions of plant material. Phytoncides are the natural volatile organic compounds extracted from plants. Sweet almond oil is an example of carrier oil, used to dilute essential oils.
Aromatherapy can be done through inhalation. By taking baths, massages and compresses, the essential oils can be absorbed by the skin. Through oral rinses and gargles, they can be absorbed through the mucous membranes. Ingestion is another method of aromatherapy.
Aromatherapy causes various therapeutic effects like the antiseptic effects, anesthetic effects, and psychological effects. Aromatherapy has its effects on the central nervous system and the metabolism. For home aromatherapy, you can blend neroli, eucalyptus, lavender, rosemary, nutmeg, and peppermints in the base oils and add a few drops of basil in that mixture. For bathing purposes, you can add oils like lavender, and rose to the water. Aromatherapy can heal depression, insomnia, acne, joint pains, stress, cough, and other types of diseases. For the skin, aromatherapy best solves acne and dry skin problems.
Aromatherapy helps to enhance the skin and makes it glow. It gives a pedicure and manicure effect, and prevents skin wrinkles. The common essential oils used for aromatherapy are sweet almond, avocado, cocoa butter, grape seed, jojoba, olive, peanut, rose hip, sesame, sunflower and more. Make sure not to use ajowan, almond, arnica, calamus, garlic, melilotus, onion, mustard, wormseed, and wormwood, without proper supervision from the aromatherapy practitioner.
The History And Future Of Massage Therapy
The Heptameron by Marguerite de Navarre is a representation of the French society in the middle ages. She has depicted various social and cultural norms of the time in the stories. Her insight into the science of medical practiced in France in the Middle Ages is quite apparent Even though the importance of medicine as specialty was acknowledged among the intellectuals of Paris; the influence of the church remained a conduit for its advancement. Although the supremacy of supernatural over natural was obvious, a clear implication was established that the natural and supernatural world was separate if not independent. As a result what we see is an amalgamation of medical science, mysticism and religion in the middle age France.
Ancient physiologists believed that the body must always have a balance of these humors, for imbalance will cause ailments. Diagnosis was based on examining sample of blood and also colors of skin, urine and feces.
Medical treatment by trained physicians rare and very expensive as a result the elite class could only afforded it. The uncertainty and unavailability of academic treatment left no choice for the general population, but to turn towards certain charms, special prayers and specific Christian rituals. Thirteen century Paris had only a half dozen doctors in public employ, with little time to spend on individual patients. Practice of medicine was not restricted to a certain sect of people rather clergy and laymen, men and women were all able to practice medicine.
The physician often compounded and dispensed drugs in addition to practicing medicine. And apothecary often engaged in medical practice as well as compounding and dispensing. It is evident from the stories in heptameron that the drugs made by apothecaries could be very lethal at times as they did not have the proper knowledge. Also personal hygiene was not an important factor for an apothecary, live alone the common people.
Diet was thought to be extremely important in the treatment of illness and prescriptions would cover the minutest of details for all sorts of conditions. The greatest general reliance was placed on broths, milk and eggs. Today the importance of diet in medical science is felt extensively. Nutrition as a special branch of study has emerged. Dietitians and nutritionist are there to help physicians in treating patients who needs special diets. Plants and herbs were used in the preparation of digestives, laxatives, emetics, diuretics, diaphoretics, styptics etc. Drugs remain to be the major form of treatments today but with the advanced technology, pharmacology has become one of the leading businesses.
Surgery a last resort advised by a physician but also it was only accessible to the wealthy. Surgery was known to be successful in cases of fistula, hemorrhoids, gangrene and cataracts. Bloodletting was one of the most common forms of surgery and was recommended for fever, inflammation, and a variety of disease condition and ironically for hemorrhages as well. There were three main methods of bloodletting during the middle ages: leeching, venesection and cupping. Among these leeching is still used, though rare as a medical procedure by some physicians. Leeching helps to reduce tissue congestion where arterial input is maintained but venous return is blocked or slowed leeches act as an extra vein to relieve a dangerous build-up of blood. As a result leech therapy is finding its way into numerous reconstructive surgeries such as digit and limb reattachment, skin graft procedure, scalp avulsions, and breast surgeries and even into effective treatment of periorbital hematomas. Anesthesia and pain relievers were available but some of the potions used were lethal in itself. For example the hemlock juice was used, and it could easily cause death.
The diseases that were very common in the Middle Ages were dysentery, jaundices pneumonia, influenza and common cold. This could be largely attributed to the living condition of that time. Rural people largely lived in a one-room structure with a central fire or hearth and a central roof with a small opening which allowed some of the smoke to escape. Homes were dark damp and cold, with minimum sunlight and poor air circulation, a perfect breeding place for germs and bacteria. The climatic conditions and life style of the time with no proper facilities contributed to the lack of personal hygiene as well. It further escalated with population growth in the towns and cities. Also due to lack of advanced techniques, patients often died due to excessive blood loss after a surgery. Today personal hygiene is considered to be a key factor to live a disease free life.
With the latest technologies available infant mortality has reduced and longevity of humans has increased tremendously compared to middle ages. As we benefit from the sophisticated technologies of medical science, it is imperative that we acknowledge the contribution of our predecessors. What we are enjoying today is the fruits from the trees whose seeds were planted by our ancestor.
Ancient physiologists believed that the body must always have a balance of these humors, for imbalance will cause ailments. Diagnosis was based on examining sample of blood and also colors of skin, urine and feces.
Medical treatment by trained physicians rare and very expensive as a result the elite class could only afforded it. The uncertainty and unavailability of academic treatment left no choice for the general population, but to turn towards certain charms, special prayers and specific Christian rituals. Thirteen century Paris had only a half dozen doctors in public employ, with little time to spend on individual patients. Practice of medicine was not restricted to a certain sect of people rather clergy and laymen, men and women were all able to practice medicine.
The physician often compounded and dispensed drugs in addition to practicing medicine. And apothecary often engaged in medical practice as well as compounding and dispensing. It is evident from the stories in heptameron that the drugs made by apothecaries could be very lethal at times as they did not have the proper knowledge. Also personal hygiene was not an important factor for an apothecary, live alone the common people.
Diet was thought to be extremely important in the treatment of illness and prescriptions would cover the minutest of details for all sorts of conditions. The greatest general reliance was placed on broths, milk and eggs. Today the importance of diet in medical science is felt extensively. Nutrition as a special branch of study has emerged. Dietitians and nutritionist are there to help physicians in treating patients who needs special diets. Plants and herbs were used in the preparation of digestives, laxatives, emetics, diuretics, diaphoretics, styptics etc. Drugs remain to be the major form of treatments today but with the advanced technology, pharmacology has become one of the leading businesses.
Surgery a last resort advised by a physician but also it was only accessible to the wealthy. Surgery was known to be successful in cases of fistula, hemorrhoids, gangrene and cataracts. Bloodletting was one of the most common forms of surgery and was recommended for fever, inflammation, and a variety of disease condition and ironically for hemorrhages as well. There were three main methods of bloodletting during the middle ages: leeching, venesection and cupping. Among these leeching is still used, though rare as a medical procedure by some physicians. Leeching helps to reduce tissue congestion where arterial input is maintained but venous return is blocked or slowed leeches act as an extra vein to relieve a dangerous build-up of blood. As a result leech therapy is finding its way into numerous reconstructive surgeries such as digit and limb reattachment, skin graft procedure, scalp avulsions, and breast surgeries and even into effective treatment of periorbital hematomas. Anesthesia and pain relievers were available but some of the potions used were lethal in itself. For example the hemlock juice was used, and it could easily cause death.
The diseases that were very common in the Middle Ages were dysentery, jaundices pneumonia, influenza and common cold. This could be largely attributed to the living condition of that time. Rural people largely lived in a one-room structure with a central fire or hearth and a central roof with a small opening which allowed some of the smoke to escape. Homes were dark damp and cold, with minimum sunlight and poor air circulation, a perfect breeding place for germs and bacteria. The climatic conditions and life style of the time with no proper facilities contributed to the lack of personal hygiene as well. It further escalated with population growth in the towns and cities. Also due to lack of advanced techniques, patients often died due to excessive blood loss after a surgery. Today personal hygiene is considered to be a key factor to live a disease free life.
With the latest technologies available infant mortality has reduced and longevity of humans has increased tremendously compared to middle ages. As we benefit from the sophisticated technologies of medical science, it is imperative that we acknowledge the contribution of our predecessors. What we are enjoying today is the fruits from the trees whose seeds were planted by our ancestor.
Are Chiropractor's Real Doctor's?
The Truth about Chiropractors
A chiropractic doctor is probably one of the most misunderstood healthcare practitioners in the medical profession. Through the years they have been looked at askance by doubters who are full of suspicion. In times past, they have been called quacks, or worse. This is due, in part, to the public's narrow and limited view of medical treatment - being that solely of administering prescription drugs and performing surgery.
As far advanced as society has become it is a pity that so many people rely so heavily on medications to "fix" their problems. The larger picture indicates that there is much more to healthcare than simply popping pills and enduring surgerical cures.
Many chiropractic patients are misguided and misinformed about the reality of their own care. For someone who has never visited a chiropractor, they may not totally grasp the ideals behind chiropractic care. The chiropractic profession makes up the largest group of health care providers practicing without administration of drugs. Additionally, in North America alone, chiropractors make up the third largest form of health care being practiced.
What Does Chiropractic Mean?
The word chiropractic itself is derived from two Greek words. The first word, cheir means hand and the second word praxis meaning done by hand. Essentially chiropractic is a precise alternative medical system that approaches wellness as a whole body experience. A chiropractor can evaluate, diagnose, classify and treat a wide range of medical problems by addressing them at their root cause without risky surgeries or pharmacology.
The relationship between the spinal column and the normal functioning of the body is an overwhelming source of knowledge. At its core beliefs, chiropractors believe that any illness is a result of a subluxation in the spine which alters the course of normal nerve function. They use adjustments or alignments that are performed by hand to realign the spine and clear up blockages.
Comparable to an MD?
Contrary to what many people believe a chiropractor endures rigorous and in depth training that compares to that of a medical doctor. A chiropractor must complete three years of pre-chiropractic schooling before they can begin their 4 year study of chiropractic care. The general student in chiropractic classes spends equal amounts studying human physiology as does a medical doctor. The total accumulation of hours necessary to complete a chiropractic degree is 4200 hours. These hours are a combination of classroom, laboratory and clinical experience.
The main difference between an MD and a Doctor of Chiropractic care is that chiropractors do not train in pharmacology or surgical procedures. The main course of study for a chiropractor is care of the spine.
Worth the Cost?
Some will assert that it costs too much to go to the chiropractor. However, the opposite is true. The fact is that oftentimes when a person is treated by a chiropractic doctor for one certain symptom, the adjustments (treatments) result in a higher level of overall health and well being. This leads to cutting back on prescription drugs, preventing the need for surgery, and slowing down the aging process.
Those who benefit from chiropractic treatments look at it as an important part of their ongoing health maintenance, similar to that of regular exercise or visiting their local health spa. They now know the difference - how they felt before chiropractic treatments and how much better they feel now.
An independents physicians association polled chiropractic patients, when asked if the patients would recommend chiropractic care to friends and family an overwhelming 95.5% said definitely "yes."
Chiropractic care is a whole health experience. Chiropractors take concern not just with the symptoms you experience but with your overall feeling of well being. They can offer you the ability to reach your level of optimum health without the harmful affects of drugs or surgery. They are more than well trained to address issues of concern and are specifically and uniquely educated to fix them
A chiropractic doctor is probably one of the most misunderstood healthcare practitioners in the medical profession. Through the years they have been looked at askance by doubters who are full of suspicion. In times past, they have been called quacks, or worse. This is due, in part, to the public's narrow and limited view of medical treatment - being that solely of administering prescription drugs and performing surgery.
As far advanced as society has become it is a pity that so many people rely so heavily on medications to "fix" their problems. The larger picture indicates that there is much more to healthcare than simply popping pills and enduring surgerical cures.
Many chiropractic patients are misguided and misinformed about the reality of their own care. For someone who has never visited a chiropractor, they may not totally grasp the ideals behind chiropractic care. The chiropractic profession makes up the largest group of health care providers practicing without administration of drugs. Additionally, in North America alone, chiropractors make up the third largest form of health care being practiced.
What Does Chiropractic Mean?
The word chiropractic itself is derived from two Greek words. The first word, cheir means hand and the second word praxis meaning done by hand. Essentially chiropractic is a precise alternative medical system that approaches wellness as a whole body experience. A chiropractor can evaluate, diagnose, classify and treat a wide range of medical problems by addressing them at their root cause without risky surgeries or pharmacology.
The relationship between the spinal column and the normal functioning of the body is an overwhelming source of knowledge. At its core beliefs, chiropractors believe that any illness is a result of a subluxation in the spine which alters the course of normal nerve function. They use adjustments or alignments that are performed by hand to realign the spine and clear up blockages.
Comparable to an MD?
Contrary to what many people believe a chiropractor endures rigorous and in depth training that compares to that of a medical doctor. A chiropractor must complete three years of pre-chiropractic schooling before they can begin their 4 year study of chiropractic care. The general student in chiropractic classes spends equal amounts studying human physiology as does a medical doctor. The total accumulation of hours necessary to complete a chiropractic degree is 4200 hours. These hours are a combination of classroom, laboratory and clinical experience.
The main difference between an MD and a Doctor of Chiropractic care is that chiropractors do not train in pharmacology or surgical procedures. The main course of study for a chiropractor is care of the spine.
Worth the Cost?
Some will assert that it costs too much to go to the chiropractor. However, the opposite is true. The fact is that oftentimes when a person is treated by a chiropractic doctor for one certain symptom, the adjustments (treatments) result in a higher level of overall health and well being. This leads to cutting back on prescription drugs, preventing the need for surgery, and slowing down the aging process.
Those who benefit from chiropractic treatments look at it as an important part of their ongoing health maintenance, similar to that of regular exercise or visiting their local health spa. They now know the difference - how they felt before chiropractic treatments and how much better they feel now.
An independents physicians association polled chiropractic patients, when asked if the patients would recommend chiropractic care to friends and family an overwhelming 95.5% said definitely "yes."
Chiropractic care is a whole health experience. Chiropractors take concern not just with the symptoms you experience but with your overall feeling of well being. They can offer you the ability to reach your level of optimum health without the harmful affects of drugs or surgery. They are more than well trained to address issues of concern and are specifically and uniquely educated to fix them
Diosmin For Circulation & Vein Benefits
Unfortunately, about half of all American women will develop varicose or spider veins at some point in their lives (2). Not only are they unsightly, these leg problems can also cause significant discomfort. Typically, varicose veins are characterized by bulging, blue, sometimes painful and inflamed veins that appear primarily in the calves and thighs. Spider veins, on the other hand, show up as a web of fine lines that can make your legs look like a road map.
While age and heredity play a role in the development of varicose and spider veins, weight gain, pregnancy, menopause and the use of hormone replacement therapy can also trigger these vein problems. Making matters worse, chronic inactivity, standing for long periods of time or habitually crossing your legs can make you more prone to injured veins (2).
Conventional treatments include surgical stripping, injecting the veins with a chemical irritant or zapping them with lasers. While these approaches can remove existing varicose or spider veins, they will not prevent new ones from developing, since these high-tech treatments do not address the underlying problem of poor circulation. Worse yet, these procedures can also cause infection, scarring, nerve damage and pain (26). If these radical treatments are not an option for you, you'll be happy to hear that there is a natural approach that not only improves the appearance of these ropy, bulging veins, it also fosters leg health to prevent future problems.
Veins Explained
To understand how varicose veins develop, you need to know a little bit about how blood moves through the body. Essentially, there are two types of major circulatory vessels in the body: the arteries, which channel blood from the heart to the extremities, and the veins, which bring blood from the extremities back to the heart. Of all the veins in your body, leg veins work the hardest to carry blood back to the heart. To accomplish this difficult task, your legs are equipped with specially designed one-way valves that keep the blood moving in the right direction. As efficiently as these valves work, your legs still fight a constant battle against the natural pull of gravity. If the veins can't move the blood efficiently or the one-way valves that prevent the blood from backwashing fail to close properly, blood collects in the legs. This pooling of blood then stretches the vein, causing swelling and injury to the vein's walls (3).
Depending on the extent of the enlargement, these veins can show up as either spider or varicose veins. Spider veins are broken capillaries and small veins that appear as jagged red, blue or purple lines on the surface of the skin. While they aren't painful, they can be extremely unattractive. Varicose veins, on the other hand, are thick veins that run deeper beneath the skin. They are far larger and much less attractive than spider veins - and they can make your legs feel fatigued, heavy, achy or even itchy. Varicose veins can also cause burning, throbbing, cramping and restlessness.
While these conditions aren't usually dangerous, severe cases can lead to chronic venous insufficiency - a persistent inability of the leg veins to adequately return blood back to the heart (4). Varicose veins are also associated with the development of skin ulcers or a chronic inflammation of a vein - a condition known as phlebitis. Phlebitis is often accompanied by formation of a blood clot, a dangerous situation since the clot can move from the leg vein and travel to the lungs (2).
Get a Leg Up with Diosmin
Your strategy for battling vein problems naturally is twofold: improving circulation and strengthening the vein walls. The first and simplest measure to improve blood flow is to counteract gravity. Standing or sitting all day makes it harder for blood to move up from the legs and back to the heart. But taking a few minutes to rest with your legs higher than your heart each day allows gravity to help return blood to the heart.
Getting in shape can also help relieve varicose and spider veins - and it can even prevent new ones from forming. As we age we lose muscle tone, which adversely affects the health of our legs. Yet adopting a consistent exercise program promotes good circulation and can help to keep our leg muscles, and the blood vessels in our legs, toned. Walking, weight training, low-impact aerobics and swimming strengthen the legs and circulatory system, and help to reduce the throbbing and aching often associated with varicose veins.
What you eat can also ease unsightly veins. A low-fat diet filled with fruits, vegetables, beans, legumes and whole grains add key nutrients and fiber to your diet. Eating a fiber-rich diet reduces the chances of constipation which can contribute to varicose veins. Constipation restricts the blood as it returns to the torso through the deep veins in the legs. Straining to have a bowel movement closes off the deep veins in the legs and restricts the flow of blood as it returns to the torso. As the blood backs up, it takes another course through superficial veins, thus the blue streaks in the legs. Eating a fiber-rich diet alleviates and prevents constipation, helping to avoid the damage to the vascular system that can result. In addition to fiber, a diet high in fruits and vegetables also ensures adequate intake of nutrients and phytonutrients, which also help tonify the blood vessels. As a bonus, a healthy diet and exercise program can also jump-start weight loss - an important consideration since carrying too much weight creates extra pressure on your heart and blood vessels, interfering with healthy circulation (2).
To strengthen the veins themselves, take a tip from the Europeans. From Austria to France to Italy, women and their doctors have relied on Diosmin for more than 30 years to treat circulatory problems affecting the legs - and with good reason. Diosmin is a unique bioflavonoid derived from citrus fruits and is closely related to other citrus bioflavonoids such as hesperiden, quercetin, and rutin (5). Clinical trials have shown that Diosmin is highly effective in boosting circulation and strengthening the veins in the legs (5). Not only does this improve existing varicose and spider veins, it can also reduce the likelihood of future problems.
What makes Diosmin so amazing is its power to specifically target the blood vessels in the legs. Diosmin improves both blood vessel elasticity and microcirculation while relieving pain and inflammation by inhibiting pro-inflammatory prostaglandins and thromboxanes (21,24). Because of its direct action on the integrity of vein walls, Diosmin also reduces the amount of fluid that leaks out of them (21,22). Diosmin's protective benefits do not stop there. Because it is a potent anti-oxidant, Diosmin decreases lipid peroxidation and reduces free radical damage that can undermine vein health (23, 27).
In one clinical trial, people who suffered from pain and swelling due to varicose veins experienced significant improvement in their symptoms after taking Diosmin for a few months (6). A review of studies also found that, among more than 5,000 patients with vein disorders, the vast majority not only saw a reduction in their discomfort, they actually saw the swelling in their calves and ankles disappear (7). Across the board, research shows that a daily dose of 500 to 1,000 mg of Diosmin improves the health of leg veins and brings tremendous relief from pain, night cramps and leg heaviness (8,9,10,11). Both short- and long-term use of this highly effective natural ingredient comes without any side effects. It is also so safe that you need not worry about adverse interactions of Diosmin with drugs, foods, lab tests or interactions with diseases or conditions. (5).
Help for Hemorrhoids
Because Diosmin reduces swelling and bolsters vein health, it can also help people suffering with hemorrhoids - those uncomfortable varicose veins that form in the lower rectum and anus. Along with making it painful to sit, hemorrhoids can itch, bleed or protrude - and almost half of all Americans suffer from them by the time they turn 50 (12). Extensive research conclusively shows that Diosmin can safely alleviate the pain, inflammation and bleeding of hemorrhoids (13,14,15). Best of all, it offers quick relief, often working its magic within a week or two (16). Plus, Diosmin reduces the risk of a relapse (17).
Diosmin for Cancer?
While no one questions Diosmin's efficacy for treating varicose and spider veins or hemorrhoids, scientists have begun exploring other ways this potent flavonoid may boost health. Their main focus - cancer prevention - especially oral and skin cancers.
Researchers haven't conclusively identified the cancer-fighting component in Diosmin, but preliminary experiments show that this flavonoid inhibits the proliferation of cancer cells (18). In two studies pitting Diosmin against other flavonoids like rutin, grapeseed extract and red wine, Spanish investigators found that Diosmin was considerably more effective at reducing the number of metastatic melanoma cells (a potentially deadly type of skin cancer cells that spread through the body) than any of the other flavonoids tested (19,20). Other studies have found that Diosmin puts the brakes on the spread of cancer cells in the mouth (25).
Although it could be years before science conclusively proves Diosmin's cancer benefit, this nutrient can't be beat for supporting vein health. Along with taking supplemental Diosmin, there are several simple strategies you can employ to encourage healthy circulation. Eating a high-fiber, anti-oxidant rich diet and getting plenty of exercise can help keep veins in top form. And remember to take a break and put your feet up every now and again.
References:
1. American Society for Dermatoloic Surgery.
2. National Women's Health Information Center. U.S. Department of Health & Human Services.
3. American College of Phlebology.
4. Society for Vascular Surgery.
5. Diosmin Monograph. Alternative Medicine Review. 2004;9(3):308-311.
6. Ting AC, et al. Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoids therapy. Vascular Surgery. 2001;35(6):443-447.
7. Ramelet AA. Daflon 500 mg: symptoms and edema clinical update. Angiology. 2005;56 Suppl 1:S25-S32.
8. Bergan JJ. Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005; 56 Suppl 1:S21-S24.
9. Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-S44.
10. Smith PC. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005; 56 Suppl 1:S33-S39.
11. Jantet G. Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assessment and quality of life improvement with micronized Flavonoids. Angiology. 2002;533:245-256.
12. National Institutes of Health.
13. Lyseng-Williamson KA, et al. Micronised purified flavonoids fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100.
14. Meshikhes AW. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surgeon. 2004;2(6):335-338.
15. Kecmanovic D, et al. PHLEBODIA (diosmine): a role in the management of bleeding nonprolapsed hemorrhoids). Acta Chirurgica Iugoslavica. 2005;52(1):115-116.
16. Diana G, et al. Activity of purified diosmin in the treatment of hemorrhoids. La Clinica Terapeutica. 2000;151(5):341-344.
17. Misra MC, et al. Randomized clinical trial of micronized flavonoids in the early control of bleeding from acute internal haemorrhoids. British Journal of Surgery. 2000;87(12):1732-1733.
18. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042.
19. Martinez C, et al. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. Journal of Agricultural and Food Chemistry. 2005;53(17):6791-6797.
20. Martinez C, et al. The effect of the flavonoids dioxmin, grapeseed extract and red wine on the pulmonary metastatic B16F10 melanoma. Histology and Histopathology. 2005;20(4):1121-1129.
21. Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56.
22. Cyrino FZ, et al. Micronization enhances the protective effect of purified flavonoidsfraction against postischaemic microvascular injury in the hamster cheek pouch. Clinical and Experimental Pharmacology & Physiology. 2004;31(3):159-162.
23. Bergan JJ, et al. Therapeutic approach to chronic venous insufficiency and its complications: place of Daflon 500 mg. Angiology. 2001;52 Suppl 1:S43-7.
24. Katsenis K. Micronized purified flavonoids fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Current Vascular Pharamcology. 2005;3(1):1-9.
25. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042.
26. National Women's Health Information Center. U.S. Department of Health and Human Services, Office on Women's Health.
27. Villa P, et al. Protective effect of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology. 1992;73:179-189.
While age and heredity play a role in the development of varicose and spider veins, weight gain, pregnancy, menopause and the use of hormone replacement therapy can also trigger these vein problems. Making matters worse, chronic inactivity, standing for long periods of time or habitually crossing your legs can make you more prone to injured veins (2).
Conventional treatments include surgical stripping, injecting the veins with a chemical irritant or zapping them with lasers. While these approaches can remove existing varicose or spider veins, they will not prevent new ones from developing, since these high-tech treatments do not address the underlying problem of poor circulation. Worse yet, these procedures can also cause infection, scarring, nerve damage and pain (26). If these radical treatments are not an option for you, you'll be happy to hear that there is a natural approach that not only improves the appearance of these ropy, bulging veins, it also fosters leg health to prevent future problems.
Veins Explained
To understand how varicose veins develop, you need to know a little bit about how blood moves through the body. Essentially, there are two types of major circulatory vessels in the body: the arteries, which channel blood from the heart to the extremities, and the veins, which bring blood from the extremities back to the heart. Of all the veins in your body, leg veins work the hardest to carry blood back to the heart. To accomplish this difficult task, your legs are equipped with specially designed one-way valves that keep the blood moving in the right direction. As efficiently as these valves work, your legs still fight a constant battle against the natural pull of gravity. If the veins can't move the blood efficiently or the one-way valves that prevent the blood from backwashing fail to close properly, blood collects in the legs. This pooling of blood then stretches the vein, causing swelling and injury to the vein's walls (3).
Depending on the extent of the enlargement, these veins can show up as either spider or varicose veins. Spider veins are broken capillaries and small veins that appear as jagged red, blue or purple lines on the surface of the skin. While they aren't painful, they can be extremely unattractive. Varicose veins, on the other hand, are thick veins that run deeper beneath the skin. They are far larger and much less attractive than spider veins - and they can make your legs feel fatigued, heavy, achy or even itchy. Varicose veins can also cause burning, throbbing, cramping and restlessness.
While these conditions aren't usually dangerous, severe cases can lead to chronic venous insufficiency - a persistent inability of the leg veins to adequately return blood back to the heart (4). Varicose veins are also associated with the development of skin ulcers or a chronic inflammation of a vein - a condition known as phlebitis. Phlebitis is often accompanied by formation of a blood clot, a dangerous situation since the clot can move from the leg vein and travel to the lungs (2).
Get a Leg Up with Diosmin
Your strategy for battling vein problems naturally is twofold: improving circulation and strengthening the vein walls. The first and simplest measure to improve blood flow is to counteract gravity. Standing or sitting all day makes it harder for blood to move up from the legs and back to the heart. But taking a few minutes to rest with your legs higher than your heart each day allows gravity to help return blood to the heart.
Getting in shape can also help relieve varicose and spider veins - and it can even prevent new ones from forming. As we age we lose muscle tone, which adversely affects the health of our legs. Yet adopting a consistent exercise program promotes good circulation and can help to keep our leg muscles, and the blood vessels in our legs, toned. Walking, weight training, low-impact aerobics and swimming strengthen the legs and circulatory system, and help to reduce the throbbing and aching often associated with varicose veins.
What you eat can also ease unsightly veins. A low-fat diet filled with fruits, vegetables, beans, legumes and whole grains add key nutrients and fiber to your diet. Eating a fiber-rich diet reduces the chances of constipation which can contribute to varicose veins. Constipation restricts the blood as it returns to the torso through the deep veins in the legs. Straining to have a bowel movement closes off the deep veins in the legs and restricts the flow of blood as it returns to the torso. As the blood backs up, it takes another course through superficial veins, thus the blue streaks in the legs. Eating a fiber-rich diet alleviates and prevents constipation, helping to avoid the damage to the vascular system that can result. In addition to fiber, a diet high in fruits and vegetables also ensures adequate intake of nutrients and phytonutrients, which also help tonify the blood vessels. As a bonus, a healthy diet and exercise program can also jump-start weight loss - an important consideration since carrying too much weight creates extra pressure on your heart and blood vessels, interfering with healthy circulation (2).
To strengthen the veins themselves, take a tip from the Europeans. From Austria to France to Italy, women and their doctors have relied on Diosmin for more than 30 years to treat circulatory problems affecting the legs - and with good reason. Diosmin is a unique bioflavonoid derived from citrus fruits and is closely related to other citrus bioflavonoids such as hesperiden, quercetin, and rutin (5). Clinical trials have shown that Diosmin is highly effective in boosting circulation and strengthening the veins in the legs (5). Not only does this improve existing varicose and spider veins, it can also reduce the likelihood of future problems.
What makes Diosmin so amazing is its power to specifically target the blood vessels in the legs. Diosmin improves both blood vessel elasticity and microcirculation while relieving pain and inflammation by inhibiting pro-inflammatory prostaglandins and thromboxanes (21,24). Because of its direct action on the integrity of vein walls, Diosmin also reduces the amount of fluid that leaks out of them (21,22). Diosmin's protective benefits do not stop there. Because it is a potent anti-oxidant, Diosmin decreases lipid peroxidation and reduces free radical damage that can undermine vein health (23, 27).
In one clinical trial, people who suffered from pain and swelling due to varicose veins experienced significant improvement in their symptoms after taking Diosmin for a few months (6). A review of studies also found that, among more than 5,000 patients with vein disorders, the vast majority not only saw a reduction in their discomfort, they actually saw the swelling in their calves and ankles disappear (7). Across the board, research shows that a daily dose of 500 to 1,000 mg of Diosmin improves the health of leg veins and brings tremendous relief from pain, night cramps and leg heaviness (8,9,10,11). Both short- and long-term use of this highly effective natural ingredient comes without any side effects. It is also so safe that you need not worry about adverse interactions of Diosmin with drugs, foods, lab tests or interactions with diseases or conditions. (5).
Help for Hemorrhoids
Because Diosmin reduces swelling and bolsters vein health, it can also help people suffering with hemorrhoids - those uncomfortable varicose veins that form in the lower rectum and anus. Along with making it painful to sit, hemorrhoids can itch, bleed or protrude - and almost half of all Americans suffer from them by the time they turn 50 (12). Extensive research conclusively shows that Diosmin can safely alleviate the pain, inflammation and bleeding of hemorrhoids (13,14,15). Best of all, it offers quick relief, often working its magic within a week or two (16). Plus, Diosmin reduces the risk of a relapse (17).
Diosmin for Cancer?
While no one questions Diosmin's efficacy for treating varicose and spider veins or hemorrhoids, scientists have begun exploring other ways this potent flavonoid may boost health. Their main focus - cancer prevention - especially oral and skin cancers.
Researchers haven't conclusively identified the cancer-fighting component in Diosmin, but preliminary experiments show that this flavonoid inhibits the proliferation of cancer cells (18). In two studies pitting Diosmin against other flavonoids like rutin, grapeseed extract and red wine, Spanish investigators found that Diosmin was considerably more effective at reducing the number of metastatic melanoma cells (a potentially deadly type of skin cancer cells that spread through the body) than any of the other flavonoids tested (19,20). Other studies have found that Diosmin puts the brakes on the spread of cancer cells in the mouth (25).
Although it could be years before science conclusively proves Diosmin's cancer benefit, this nutrient can't be beat for supporting vein health. Along with taking supplemental Diosmin, there are several simple strategies you can employ to encourage healthy circulation. Eating a high-fiber, anti-oxidant rich diet and getting plenty of exercise can help keep veins in top form. And remember to take a break and put your feet up every now and again.
References:
1. American Society for Dermatoloic Surgery.
2. National Women's Health Information Center. U.S. Department of Health & Human Services.
3. American College of Phlebology.
4. Society for Vascular Surgery.
5. Diosmin Monograph. Alternative Medicine Review. 2004;9(3):308-311.
6. Ting AC, et al. Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoids therapy. Vascular Surgery. 2001;35(6):443-447.
7. Ramelet AA. Daflon 500 mg: symptoms and edema clinical update. Angiology. 2005;56 Suppl 1:S25-S32.
8. Bergan JJ. Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005; 56 Suppl 1:S21-S24.
9. Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-S44.
10. Smith PC. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005; 56 Suppl 1:S33-S39.
11. Jantet G. Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assessment and quality of life improvement with micronized Flavonoids. Angiology. 2002;533:245-256.
12. National Institutes of Health.
13. Lyseng-Williamson KA, et al. Micronised purified flavonoids fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100.
14. Meshikhes AW. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surgeon. 2004;2(6):335-338.
15. Kecmanovic D, et al. PHLEBODIA (diosmine): a role in the management of bleeding nonprolapsed hemorrhoids). Acta Chirurgica Iugoslavica. 2005;52(1):115-116.
16. Diana G, et al. Activity of purified diosmin in the treatment of hemorrhoids. La Clinica Terapeutica. 2000;151(5):341-344.
17. Misra MC, et al. Randomized clinical trial of micronized flavonoids in the early control of bleeding from acute internal haemorrhoids. British Journal of Surgery. 2000;87(12):1732-1733.
18. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042.
19. Martinez C, et al. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. Journal of Agricultural and Food Chemistry. 2005;53(17):6791-6797.
20. Martinez C, et al. The effect of the flavonoids dioxmin, grapeseed extract and red wine on the pulmonary metastatic B16F10 melanoma. Histology and Histopathology. 2005;20(4):1121-1129.
21. Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56.
22. Cyrino FZ, et al. Micronization enhances the protective effect of purified flavonoidsfraction against postischaemic microvascular injury in the hamster cheek pouch. Clinical and Experimental Pharmacology & Physiology. 2004;31(3):159-162.
23. Bergan JJ, et al. Therapeutic approach to chronic venous insufficiency and its complications: place of Daflon 500 mg. Angiology. 2001;52 Suppl 1:S43-7.
24. Katsenis K. Micronized purified flavonoids fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Current Vascular Pharamcology. 2005;3(1):1-9.
25. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042.
26. National Women's Health Information Center. U.S. Department of Health and Human Services, Office on Women's Health.
27. Villa P, et al. Protective effect of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology. 1992;73:179-189.
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